Cracking the Ketamine Code

Treatment-resistant depression affects nearly 3 million people in the United States. In the early 2000s, researchers began looking at ketamine as a possible treatment. Decades of research supported by the National Institute of Mental Health led to the 2019 approval of esketamine for treatment-resistant depression.

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CTE identified in brain donations from young amateur athletes

McKee AC, et al. “Neuropathological and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts.” August 28, 2023. JAMA Neurology. DOI: 10.1001/jamaneurol.2023.2907

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Likely cause of Alzheimer’s identified in new study

  • Worldwide, Alzheimer’s disease is one of the most common forms of dementia.
  • Using mouse models, researchers in Australia have identified one of the likely causes of Alzheimer’s disease. Some have dubbed the finding a “breakthrough.”
  • By studying the blood-brain barrier, the scientists have come away with a better understanding of why and how Alzheimer’s disease occurs.
  • Their findings suggest potential treatment and prevention options for the neurodegenerative condition.

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How can computer models help us better understand the brain?

Welcome to the Brain Experts podcast, where we meet neuroscience experts and talk about their work, the field in general, and where it’s going. We hope to provide both education and inspiration. I am Peter Bandettini with the National Institute of Mental Health. Please note that the views expressed by the guests do not reflect NIMH policy. This is episode three with Niko Kriegeskorte. We will discuss, among other things, how might brain imaging help us to truly understand the brain. Let’s chat.

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The Amazing Brain: Mapping Brain Circuits in Vivid Color

Hop aboard as we fly up, down, left, and right through the information highways of the human brain! This captivating and eye-catching video was one of the winners of the 2019 “Show us Your Brain!” contest sponsored by the NIH-led Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative.

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The Amazing Brain: Zooming Through the Globus Pallidus Externa

The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative continues to find new ways to visualize neurons interconnecting into the billions of circuits that control our thoughts, feelings, and movements. This video, another winner in the initiative’s “Show Us Your Brain!” contest, offers a beautiful example of how these imaging techniques are getting better all the time.

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Brain Basics: Know Your Brain

The brain is the most complex part of the human body. This three-pound organ is the seat of intelligence, interpreter of the senses, initiator of body movement, and controller of behavior. Lying in its bony shell and washed by protective fluid, the brain is the source of all the qualities that define our humanity. The brain is the crown jewel of the human body.

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